Anti-inflammatory activity of Guduchi Ghana (aqueous extract of Tinospora Cordifolia Miers.)

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Alkaloids from Tinospora Cordifolia Miers

The details of isolation and spectral analysis of the protoberberine alkaloids, tetrahydropalmatin and jatrorrhizine, reported for the first time to occur in the roots of Tinospora cordifolia by the authors, are described.

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Extracts of Tinospora cordifolia (TCE) have been shown to possess anti-tumor properties, but the mechanism of the anti-tumor function of TCE is poorly understood. This investigation elucidates the possible mechanism underlying the cytotoxic effects of dichlormethane extracts of TCE, after selecting optimal duration and concentration for treatment. HeLa cells were exposed to various concentratio...

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Seasonal variations in physicochemical profiles of Guduchi Satva (starchy substance from Tinospora cordifolia [Willd.] Miers)

Guduchi Satva (GS), the starchy material extracted from the Guduchi stem is well-known Ayurvedic single drug formulation having a wide range of therapeutic utility. Species of the plant, stem size, collection time, season and maturity of the plant may affect the yield and physico-chemical profile of GS. However, published data on such variations is lacking. Considering this, present study is pl...

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Effect of aqueous extract of Tinospora cordifolia on

18 BACKGROUND: The current practice of ingesting phytochemicals to support the immune 19 system or to fight infections is based on centuries-old tradition. Macrophages are involved at all 20 stages of the immune response. The present study focuses on immunostimulant properties of 21 Tinospora cordifolia in circulating macrophages of CCl4 (0.5 ml/kg body weight) intoxicated 22 male albino mice. ...

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Immunomodulatory effects of Tinospora cordifolia (Guduchi) on macrophage activation

Macrophages are the first line of defense and constitute important participants in the bi-directional interaction between innate and specific immunity. Macrophages are in a quiescent form and are activated when given a stimulus. In the present study, we have used Tinospora cordifolia, commonly known as Guduchi, to see its effect on macrophage activation. The direct drug treatment to J774A cells...

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ژورنال

عنوان ژورنال: AYU (An International Quarterly Journal of Research in Ayurveda)

سال: 2014

ISSN: 0974-8520

DOI: 10.4103/0974-8520.141958